If you take a GLP-1 medication such as Ozempic, Wegovy, Mounjaro or Zepbound, clinicians suggest a few Thanksgiving habits: start with small portions and check in with how you feel, put protein (turkey or ham) and vegetables on the plate first, eat slowly, go easy on fried and very rich foods that can worsen nausea or fullness, limit alcohol, and keep drinking water. Spreading food across the day can help more than one huge plate. Follow your prescriber's specific advice.
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GLP-1 medicines slow stomach emptying and reduce appetite. A plate that used to be normal can now feel like too much, and rich, fatty or fried foods may make nausea and fullness worse for some people. That doesn't mean skipping the holiday — it means planning the plate.
A practical plate: a palm-sized portion of turkey or ham, a spoonful of two favorite sides, a vegetable, and dessert as a few bites later rather than right after the meal. Leftovers are your friend — the meal doesn't have to happen all at once. For the rest of the week, our GLP-1 meal plan and free 7-day GLP-1 meal plan cover everyday eating, and the Wegovy meal plan builds a week from your care team's targets.
Skip the risk entirely: SmashMeals' Complete Thanksgiving Dinner comes from a dedicated gluten-free kitchen — smoked turkey or ham, four sides, gluten-free gravy, rolls, cranberry sauce and pie. $159 feeds 6, $279 feeds 12. Shipped orders close Thursday, November 19 at 11:59 PM Eastern.
Yes. Clinicians generally suggest smaller portions, protein and vegetables first, eating slowly, limiting fried and very rich foods and alcohol, and staying hydrated. Follow your prescriber's advice.
GLP-1 medications slow stomach emptying, so large, high-fat or fried meals may increase fullness, nausea or reflux for some people.
Do not change your dose or schedule without talking to your prescriber.
It is a traditional holiday meal, so portion it to your appetite. Smoked turkey and ham are protein-forward, and the meal comes from a dedicated gluten-free kitchen. Leftovers reheat well across the week.
This guide is general information, not medical advice. Follow your prescriber's and care team's guidance.
See the 2026 gluten-free Thanksgiving menu · Order Thanksgiving dinner
By Lew Kizer, founder of SmashMeals. "Whatever you do, do it from the heart, as something done for the Lord and not for people." Colossians 3:23 (CSB)