In the STEP 1 body-composition substudy, lean tissue accounted for roughly a third to 40% of total weight lost on semaglutide; fat mass fell proportionally more. Protein and resistance training are the levers clinicians most often recommend. SmashMeals entrées are protein-forward and 100% gluten-free, with exact grams on every label.
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There is no single correct protein number for everyone taking a GLP-1. The adult Recommended Dietary Allowance is 0.8g per kg of body weight per day, and clinicians commonly recommend more than the RDA during intentional weight loss to help support lean mass. Weight lost on a GLP-1 is a mix of fat and lean tissue: in the STEP 1 DXA body-composition substudy, fat mass fell proportionally more than lean mass, with published analyses putting lean tissue at roughly a third to 40% of the total lost. Adequate protein plus resistance training are the levers most often recommended — neither guarantees you keep every pound of muscle.
Reviewed August 27, 2026 by the SmashMeals editorial team against current FDA prescribing information and NIH/NIDDK guidance. Nutrition information, not medical advice — meal tolerance and nutrition needs vary, so follow your prescriber's or dietitian's guidance.
SmashMeals is a food company, not a medical provider. Ozempic and Wegovy are registered trademarks of Novo Nordisk; Mounjaro and Zepbound are registered trademarks of Eli Lilly. We are not affiliated with, endorsed by, or sponsored by either manufacturer.
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